Are clinical trials complex projects?

Document Type : Narrative Review

Authors

1 Faculty of Pharmacy and Biochemistry, National University of San Marcos, Lima, Peru

2 Faculty of Psychology, Pontifical Catholic University of Peru, Lima, Peru

3 Department of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran

10.22034/mnba.2023.408289.1038

Abstract

Clinical trials are research projects that are performed on human subjects to determine the efficiency of certain medical or behavioral interventions or therapy. This review will focus on a few of the most critical differences between straightforward projects and those that include a higher level of complexity. A complicated endeavor can have a variety of connotations for various individuals. One further measure that may be utilized to quantify the level of complexity that the task entails is the number of individual interactions that are necessary to complete it. The greater the number of functional units that interact with one another, the more complicated the integration will be. When functional units are dispersed around the globe and when differences in cultural norms make it difficult for them to interact with one another, things can become complicated very quickly. When the scope, cost, and length of the project are all larger, it is more likely that changes in the scope will influence the budget and the timeline. Cost and time overruns are more likely to occur in clinical projects that are larger and more complicated. The co-clinical projects decrease the disparity available between pre-clinical investigations and clinical trials. Emerging data such as artificial intelligence from closed sub-protocols have the potential impact on the conduct of ongoing studies in the case of biomedicine and nanomedicine. Furthermore, in this review, we have discussed current nanomedicine in the clinical stages.

Graphical Abstract

Are clinical trials complex projects?

Highlights

  • It is standard practice to look into a variety of medications, experiment with a range of administration methods, and look into a variety of locations throughout the world.
  • In contrast to conventional clinical trials, co-clinical projects decrease the disparity available between pre-clinical investigations and clinical trials.
  • Cost and time overruns are more likely to occur in clinical projects that are larger and more complicated.
  • The clinical trials in both medicine and nanomedicine are currently at an intriguing juncture.

Keywords

Main Subjects

Rights and permissions

© 2023 by the MNBA. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

Micro Nano Bio Aspects
Volume 2, Issue 3 - Serial Number 3
September 2023
Pages 13-23

Files

History

  • Receive Date: 23 July 2023
  • Revise Date: 19 August 2023
  • Accept Date: 19 August 2023

Share

How to cite

Statistics