%0 Journal Article %T Relationship between MOX genes and antibiotic resistance in Klebsiella pneumoniae strains in nosocomial infections %J Micro Nano Bio Aspects %I Birkar Publisher %Z 2980-8081 %A Amraei, Shokouh %A Eslami, Gita %A Taherpour, Arezou %A Hashemi, Ali %D 2022 %\ 08/01/2022 %V 1 %N 2 %P 12-17 %! Relationship between MOX genes and antibiotic resistance in Klebsiella pneumoniae strains in nosocomial infections %K Nosocomial infections %K Hospitalized Patients %K Extended-Spectrum Beta-Lactamases %K Therapeutic options %K Pneumonia infections %K Intra-abdominal infections %R 10.22034/mnba.2022.155320 %X Drug resistance in microorganisms, specifically bacteria pathogens, is a serious threat to patients worldwide. Multidrug-resistance of bacteria to a broad spectrum of conventional antibiotics is the main hindrance to treating patients admitted to hospital. In this case, the increased emergence of multidrug-resistance mechanisms among Klebsiella pneumoniae nosocomial infections has limited the therapeutic options for treating bacterial infections such as intra-abdominal, urinary tract, and pneumonia infections. The beta-lactamase enzymes in these bacteria, as extended-spectrum beta-lactamases (ESBL), are the primary defense of gram-negative bacteria against a wide range of beta-lactam antibiotics. This review aimed to evaluate the role of MOX genes in the antibiotic resistance of K. pneumoniae strains isolated from hospitalized patients. %U https://www.mnba-journal.com/article_155320_750dd90ca5850670f47837b3067ab26a.pdf